Despite its immense potential, North Africa suffers from significant national and transnational issues that threaten the region’s long-term stability and prosperity. These transnational challenges require transnational solutions, but past attempts to integrate the region have accomplished little. The United States’ fragmented policy approach to North Africa has failed to improve the situation and has often exacerbated it. While North Africa does not rank first in U.S. policy priorities, the United States has a vested interest in helping create a North Africa that is stable, prosperous, connected, and integrated with the international community. Achieving this goal will require U.S. leadership and a clear, unified regional strategy that makes maximum use of U.S. resources in concert with those of European and African partners.